Panacea CoffeeHouse, Cafe and Roastery - Cafe in Waynesville
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Panacea CoffeeHouse, Cafe and Roastery

Waynesville•66 Commerce St Waynesville NC 28786
9.5
Outstanding

Best For

Coffee lovers • Remote workers • Families

Pro Tip

Try the locally roasted beans and sit by the creek for the best ambiance

About Panacea CoffeeHouse, Cafe and Roastery

Brick-walled coffee shop in a former warehouse offering premium roasts, breakfast & sandwiches.

Amenities & Features

Exceptional outdoor patio seating with creek/river viewsHouse-roasted coffee including organic Guatemala dark roast with excellent flavorVersatile atmosphere perfect for studying, business meetings, or casual hangoutsPopular food items including wraps and the Wakey Wakey breakfast sandwich on sourdough

Visitor Sentiment

Based on reviews

Panacea CoffeeHouse, Cafe and Roastery receives consistently positive feedback from visitors. Located in Waynesville, it's a solid choice for the area.

Panacea CoffeeHouse, Cafe and Roastery Opening Hours

Monday8:30 AM to 3:30 PM
Tuesday8:30 AM to 3:30 PM
Wednesday8:30 AM to 3:30 PM
Thursday8:30 AM to 3:30 PM
Friday8:30 AM to 3:30 PM
Saturday8:30 AM to 3:30 PM
Sunday8:30 AM to 3:30 PM

Best Times to Visit Panacea CoffeeHouse, Cafe and Roastery

For the best dining experience, consider making reservations for weekend evenings.

🔥Buzzing
Weekend dinner rush 5PM - 8PM
☀️Relaxed
Tuesday & Wednesday evenings

Tags

Highly Reviewed

Frequently Asked Questions

What are the hours for Panacea CoffeeHouse, Cafe and Roastery?

Check our opening hours section for current times. Hours may vary seasonally.

Is Panacea CoffeeHouse, Cafe and Roastery family-friendly?

Yes, Panacea CoffeeHouse, Cafe and Roastery welcomes visitors of all ages. It's a popular destination for families visiting Waynesville.

How do I get to Panacea CoffeeHouse, Cafe and Roastery?

Panacea CoffeeHouse, Cafe and Roastery is located at 66 Commerce St Waynesville NC 28786. Use the directions button for navigation.

Does Panacea CoffeeHouse, Cafe and Roastery take reservations?

We recommend calling ahead or checking their website for reservation options, especially on weekends.

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Contact Restaurant

Call ahead for reservations

We recommend calling ahead for weekend reservations

TSM Verified
9.5/10

We use a weighted 10-point scoring system to evaluate the best places to visit and things to do in the Smokies.

Scoring is carefully evaluated based on reviews, social signals and expert assessments.

✨Food Quality
8.90
👤Service
8.84
🏛️Ambience
8.78
💰Value
8.62
Public Review Sentiment
Based on 709 Reviews

Panacea CoffeeHouse, Cafe and Roastery receives consistently positive feedback from visitors. Located in Waynesville, it's a solid choice for the area.

Last Updated Jan 1, 2026

Call Website
Directions
Address

66 Commerce St Waynesville NC 28786

66 Commerce St Waynesville NC 28786

Waynesville

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